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⠀⠀⠀⠀Hybrid polyion complexes (HPICs) are formed by adding metal ions to a double-hydrophilic block copolymer leading to highly monodisperse polymer based nano-objects. HPICs provide an opportunity to combine attributes of the hydrophilic polymer, among them compatibility with biological systems, with properties of the inorganic ions. Working closely with collaborators at the Université de Toulouse, are developing HPIC’s as innovative medical imaging contrast agents.
Representative Publications
“Hybrid Polymeric Nanostructures Stabilized by Zirconium and Gadolinium ions for Use as Magnetic Resonance Imaging Contrast Agents” Marjorie Yon, Stéphane Gineste, Giacomo Parigi, B. Lonetti, Laure Gibot, Daniel R. Talham, Jean-Daniel Marty, Christophe Mingotaud ACS Appl Nano Mater. 2021, 4, 4974–4982 https://doi.org/10.1021/acsanm.1c00495